Dr. Mario 64 is a puzzle game for the Nintendo 64 platform, released by Nintendo in North America in 2001. As a sequel to the classic Dr. Mario, it retains the core gameplay of the original: players control Dr. Mario to throw two-colored capsules and eliminate red, yellow, and blue viruses inside the bottle. By rotating and moving capsules to line up four or more matching elements horizontally or vertically, players can clear the viruses. The game offers multiple modes, including single-player challenges and multiplayer battles for up to four players, boosting interactivity and fun. It also introduces characters like Wario to enrich the content. Notably, Dr. Mario 64 was released in mainland China as a simplified Chinese version for the iQue Player, titled Dr. Mario.
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