Bio F.R.E.A.K.S. is a 3D fighting game released by Midway in 1998 for PlayStation, Nintendo 64, and Windows. Set in the futuristic Neo-Amerika amid rapid tech and bioengineering advances, corporate conflicts spark the Techno-Industrial Civil Wars, collapsing the economy and pushing states to secede. To end the chaos and reunify the nation, the Secret Games Commission hosts a fighting tournament where corporate representatives compete for territorial control. Fighters are called Bio F.R.E.A.K.S.—short for Biological Flying Robotic Enhanced Armored Killing Synthoids. The game features 8 playable characters and 2 hidden bosses, each with unique weapons and abilities like pulse lasers, grenade launchers, stun guns, swords, and machine guns. Battles take place in fully 3D, multi-tiered arenas where players can move freely, fly with jetpacks, and attack mid-air. Hazards such as lava pits, meat grinders, and spinning blades add intensity. Blending melee and ranged combat, each character has multiple special moves and "Fatalities" that deal lethal damage and can even dismember opponents. Its high freedom and deep combat system made it stand out among fighting games of its era.